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CASE57
CASE 50: MRI Brain
55M, convulsions
Diagnosis
Gliobastoma Multiforme with spread along white matter tracts
PEARLS
the most common adult primary intracranial neoplasm, and has the worst prognosis
association with p53 mutation related?syndromes such as NF1?
typically poorly-marginated, diffusely infiltrating necrotic masses?
?
varied appearance on MRI but usually hypo-iso (T1) and hyper (t2/FLAIR), enhance vividly, with significant edema, mass effect, and also hemorrhage
Typical appearance as of tumors on MRS with increase in choline and lactate?
Poor prognosis - average survival after discovery is 12-18 months
Answer is RIGHT
Answer is WRONG
GENDER
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