|Case 14 :|
Young female with uncontrolled hypertension.
What is the diagnosis?
|__________SCROLL FOR ANSWER__________|
Juxtaglomerular Cell tumor.
It is a benign renal tumour and a curable cause of hypertension, that should be included in the differential diagnosis of any patient with hyperreninemic hypertension regardless of the age. However, these tumors usually occur in a relatively young age group, with a mean age of 24 years. It produces a clinical syndrome characterized by hypertension, elevated plasma renin activity, secondary hyperaldosteronism, and hypokalemia that is reversed by resection of the tumour
The tumour is usually small, well-circumscribed and encapsulated. Biological behaviour is benign, although complications of hypertension may prove to be lethal.
Treatment is by partial
nephrectomy. No reports of recurrence, metastases, or malignant