URORADIOLOGY


Case 14 :
History: Young female with uncontrolled hypertension.
What is the diagnosis?
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Diagnosis

Juxtaglomerular Cell tumor.

Discussion

It is a benign renal tumour and a curable cause of hypertension, that should be included in the differential diagnosis of any patient with hyperreninemic hypertension regardless of the age. However, these tumors usually occur in a relatively young age group, with a mean age of 24 years. It produces a clinical syndrome characterized by hypertension, elevated plasma renin activity, secondary hyperaldosteronism, and hypokalemia that is reversed by resection of the tumour

The tumour is usually small, well-circumscribed and encapsulated. Biological behaviour is benign, although complications of hypertension may prove to be lethal.

Treatment is by partial nephrectomy. No reports of recurrence, metastases, or malignant
transformation has been noted.

DR RAVI KADASNE
kadasne@emirates.net.ae